You’ve already done large-scale conquests and religion/holy goals—these three push that further by taking a Timurid start to Mughal domination, forcing early aggressive expansion into Asian grasslands as Kale, and then stretching your late-game imperial skill to the absurd with Ryukyu world-ownership, giving a clear ramp-up in complexity and different playstyles while building on your proven ability to blaze through big, ambitious goals.

You’ve already done huge regional and religious runs (Mare Nostrum, Dar al-Islam, Saladin’s Legacy and Master of India), so pushing into Persia/Armenia to form Persia (or Eranshahr) and the Ardabil start plus the Karabakh Coptic-border conversion objective form a coherent next set that builds on your experience conquering, coring and converting in the Middle East region.