You've already unlocked lots of maritime, trade and colonial achievements (World Discoverer, Trade Hegemon, All Your Trade Are Belong to Us, The Grand Armada, This navy can take it all and That is mine!), so pushing toward continent-spanning European dominance as Portugal (All Blue) and early global footholds (The Navigator) fits your playstyle and skillset. These two pair naturally — Portugal’s early exploration makes The Navigator straightforward and getting Europe under blue allies/subjects is a clear next strategic target. I included Trade Hegemon to reinforce your existing trade-focused play (you already have Trade Hegemon unlocked which shows you like trade control), but replacing that with a complementary goal keeps your progression focused on exploration → trade dominance → continental influence.

A starter chain built with the onboarding wizard.

There are two: Shemot is Not and Hanukkah Mutapa

Shemot means Names. And it's the name of the book of Exodus.

Hanukkah Mutapa. Technically, same idea as above.

Diplomacy-centric early game transitioning into full Mediterranean conquest, with end goal to achieve Mare Nostrum.

Austria starts as HRE Emperor with one of the strongest mission trees in the game — fill your forcelimit first, the road ahead is long.

This is another sample/funny/meme chain that oversimplifies what needs to be done to conquer whole world in EU4.

Diplomacy-centric run as Austria with end goal to form HRE.

Form Italy as Naples and conquer entire Mediterranean and Black sea coastline.

Poland finds itself in a very strong position in terms of total development at the beginning of the game to dominate whole Europe and the world. Having Lithuania as a subject that eventually will be integrated into the Commonwealth is another strong argument to that.

Geographically it isn't as well protected as it could be, and therefore we need to ensure that our southern and eastern borders are taken care of.

Start with weakining Ottomans by taking Constantinople/subjugating Byzantium, and therefore preventing them from using their jumpstart into expansion. Then use the dividedness of your eastern neighbours and their initial dependence on Golden Horde to cripple them even more and prevent from unification to secure this flank as well.

This chain deserves to be extended with more steps and maybe also chained together with Victoria 3 and HOI.

Suggested path to form Germany as Brandenburg, following a historically inspired progression.